These are a special class of tumours called paragangliomas found in the neck at the junction of the blood vessels feeding your neck and brain. These are rare occurring in about 1 in 50,000 population with approximately 85% sporadic in origin. Multiple cases can be seen in running in families(10 -15%), people living in high altitude regions and those of African descent.
These are slow growing in nature and usually become noticeable in the 20 – 50 year age group. Some of these tumours actively secrete chemicals which may cause elevation in blood pressure.
They are typically seen as a painless neck swelling which is slow growing and are sometimes diagnosed while being examined for other illness.
Imaging studies like CT angiogram or MR angiogram are done to see the size of the tumour and its relation to the various structures in the neck. These tumour are known to spread locally and often involve the blood vessels feeding the brain and face completely along with vital nerves and veins.Rarely these tumors are malignant(5%) with distant metastasis. These tumors sometimes release chemicals which can cause increased blood pressure and a test to confirm that may be done if clinically indicated.If catacholamine levels are elevated, an evaluation for adrenal pheochromocytomas should be performed. If detected these tumors should be removed prior to the carotid surgery. FNAC or biopsy is not indicated in majority of cases as imaging is diagnostic.
Surgical excision is the main modality of treatment and the higher the grade of tumour the more difficult the surgery is with risk of involvement of other structures.
Such patients are at a high risk of carotid resection due to the tumor’s involvement. There are risks of cranial nerve injuries (IX, X, XI, XII), bleeding, infection, the possibility of a carotid bypass with vein grafts, stroke.
Embolization of carotid body tumors has been a controversial topic. It has been recommended by some centres when the size of the tumor exceeds 4 cm in size. Blood loss appears to be less with prior embolization of larger tumors but has not been found to be true across all studies.
Post operative recovery
Typically some sorethroat and voice change may be seen for 2 to 5 days which gradually recovers over a week. For patients with nerve involvement with higher grade tumours, nerve excision may produce changes with voice and swallowing which can be recovered with therapy over 6 – 8 weeks.
About Vascular Centre Bangalore
Vascular & Endovascular surgery is a speciality that is relatively new in most of India and the Indian subcontinent.